Genetic risk of Alzheimer’s disease is linked to short sleep duration

Short duration of sleep increases risk of colorectal adenoma.

BACKGROUND Short duration and poor quality of sleep have been associated with increased risks of obesity, cardiovascular disease, diabetes mellitus, and total mortality. However, few studies have investigated their associations with risk of colorectal neoplasia. METHODS In a screening colonoscopy-based case-control study, the Pittsburg Sleep Quality Index (PSQI) was administered to 1240 study...

Short sleep duration in infancy and risk of childhood overweight.

OBJECTIVE To examine the extent to which infant sleep duration is associated with overweight at age 3 years. DESIGN Longitudinal survey. SETTING Multisite group practice in Massachusetts. PARTICIPANTS Nine hundred fifteen children in Project Viva, a prospective cohort. Main Exposure At children's ages 6 months, 1 year, and 2 years, mothers reported the number of hours their children slept...

Short Sleep Duration Is Associated with Risk of Future Diabetes but Not Cardiovascular Disease: a Prospective Study and Meta-Analysis

Epidemiologic studies have observed association between short sleep duration and both cardiovascular disease (CVD) and type 2 diabetes, although these results may reflect confounding by pre-existing illness. This study aimed to determine whether short sleep duration predicts future CVD or type 2 diabetes after accounting for baseline health. Baseline data for 241,949 adults were collected throu...

Serotonergic dysregulation is linked to sleep problems in Parkinson's disease

Insomnia with objective short sleep duration is associated with a high risk for hypertension.

STUDY OBJECTIVES To examine the joint effect of insomnia and objective short sleep duration on hypertension risk. DESIGN Representative cross-sectional study. SETTING Sleep laboratory. PARTICIPANTS 1,741 men and women randomly selected from central Pennsylvania. INTERVENTIONS None. MEASUREMENTS Insomnia was defined by a complaint of insomnia with a duration > or = 1 year, while poor s...